Active ingredients can present limitations due to their physicochemical properties.

Some of them can be too hydrophilic, which makes it difficult for them to penetrate the lipophilic stratum corneum, resulting in low absorption, or poorly bioavailable in skin layers.

Even the most effective ingredients do not work without a proper skin absorption. 

To overcome this limitation, active ingredients can be vehiculated using delivery systems with skin-like structures, which facilitate their interaction with the skin barrier.

These systems help enhance absorption, improve stability, and increase the bioavailability of the active compounds within the skin in an usable form for skin cells.

From its extended know-how, Sinerga presents 3 main types of vehiculation, to enhance its actives' absorption, bioavailability and efficacy:

• ACTI GPC: active ingredients are delivered through GPC (GlyceroPhosphoCholine), which acts as a biomimetic carrier whose structure is related to phospholipids that make up skin cell membranes, improving active's penetration.
• LIPO.AMI.ACI: based on the creation of an amphiphilic carrier that has high affinity with skin lipids and binds well with actives, increasing the bioavailability with its fatty acids tail and solving the problem of too hydrophilic actives.  
• ENCAPSULATION: it does not rely on molecular association like the previous, but on physical containment inside a carrier structure made of vescicles to preserve the active from degradation, oxidation or hydrolysis.

All these 3 technologies are able to solve problems linked to physico-chemical properties of the active or enhance its delivery and absorption, increasing its effect on skin. 

• Sinerga's ingredients vehiculated in GPC: Acticolina LV - ChitorepairGPC.
• Sinerga's ingredients vehiculated with LIPO.AMI.ACI: HydroxyPro-Lift - Tricho-Solve
• Sinerga's ingredients encapsulated: Eyedren - X-Solve - Tri-Solve P

Discover our delivery technologies through the Vehiculated ingredients' kit: 5 innovative formulations featuring effective claims, appealing textures, and high-value ingredient combinations for the market.